Combined Net Product Revenue: $1.646 billion for 2024, representing 33% growth compared to 2023. TTR Franchise Revenue: $343 million in Q4 2024, a 35% increase compared to Q4 2023. Full Year TTR Revenue: $705 million in the US, a 39% increase compared to 2023. Rare Franchise Revenue: $108 million in Q4 2024, an 18% increase